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Physician Pittsburgh The Puzzle People: Memoirs of a Transplant Surgeon by Thomas E. Starzl, X Given the tensions and demands of medicine, highly successful physicians and surgeons rarely achieve equal success as prose writers. It is truly extraordinary that a major, international pioneer in the controversial field of transplant surgery should have written a spellbinding, and heart-wrenching, autobiography. Thomas Starzl grew up in LeMars, Iowa, the son of a newspaper publisher and a nurse. His father also wrote science fiction and was acquainted with the writer Ray Bradbury. Starzl left the family business to enter Northwestern University Medical School where he earned both an M.D. and a Ph.D. While he was a student, and later during his surgical internship at the Johns Hopkins Hospital, he began the series of animal experiments that led eventually to the world's first transplantation of the human liver in 1963. Until the age of thirty-three, Starzl says, "I felt like a missile looking for a trajectory". His work with liver transplantation gave him a course for life and, despite initial setbacks and failures, he has pursued it relentlessly, eventually achieving stunning success. Throughout his career, first at the University of Colorado and then at the University of Pittsburgh, he has aroused both worldwide admiration and controversy. His technical innovations and medical genius have revolutionized the field, but Starzl has not hesitated to address the moral and ethical issues raised by transplantation. In this book he clearly states his position on many hotly debated issues including brain death, randomized trials for experimental drugs, the costs of transplant operations, and the system for selecting organ recipients from among scores of desperately ill patients. There aremany heroes in the story of transplantation, and many "puzzle people", the patients who, as one journalist suggested, might one day be made entirely of various transplanted parts. They are old and young, obscure and world famous.
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